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A Comprehensive Approach to Research and Innovation

Lorena Anderson

Bacteria Use the Physics of Twist to Measure Their Own Size and Shape

Theoretical physics Professor Ajay Gopinathan has been working over the past decade to model a submicroscopic mystery. Now, he and a team of colleagues have verified an important piece of the puzzle of how tiny, intrinsically twisted protein filaments responsible for repairing and growing cells know where to go to perform their function.

The work could someday enable scientists to control bacterial growth.

Human Waste Treatment Helps Solve Climate-Change Puzzle, New Study Shows

About 4.5 billion people around the globe do not have access to adequate sanitation, and what they do have — typically pit latrines and lagoons — are responsible for widespread illnesses and a portion of the greenhouse gases that are warming the planet.

UC Merced Professor Rebecca Ryals and a group of colleagues have a solution that not only increases safety, sustainability and jobs, but reduces greenhouse gas emissions and waste-borne illnesses while producing an effective fertilizer for agriculture.

At the Intersection of Math and Biology, Sindi Lab Sees a Breakthrough in Prion Disease

A UC Merced researcher and her lab have unlocked one of the mysteries that could lead to treatments — or even cures — for prion diseases in mammals.

Prion diseases are a family of rare, progressive neurodegenerative disorders that affect both humans — such as with Creutzfeldt-Jakob disease or fatal familial insomnia — and animals, such as mad-cow disease. These disorders are usually rapidly progressive and always fatal, according to the Centers for Disease Control.

Researchers Discover Mechanism Proteins Use To Find And Control Genes

Bioengineering Professor Victor Muñoz has answered a long-standing genetic mystery, and his research suggests that someday, bioengineers could devise ways to control gene activity — manually switching off the genes that contribute to cancer, for instance.

“If this mechanism turns out to be as powerful as we anticipate, engineering it will be relatively straightforward,” Muñoz said. “Controlling the output of genes could be done in a targeted way by new genome editing technologies such as CRISPR.”

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