Current work focuses on a number of topics including:
Applying our research findings to engineer proteins with altered functionality to serve as templates for potential therapeutic targets, and to the biotechnological application of protein molecular platforms and ultra-structures.
Cardiovascular diseases are the leading cause of human death all over the world. My laboratory have been focused in understanding molecular and cellular mechanisms involved in the development of cardiac arrhythmias during an increase in the heart rate (tachycardia) and after a cardiac infarction (ischemia).
Controlling the development of this cardiac arrhythmias will dramatically improve the rate of survival after a cardiac episode.
The majority of work focuses on understanding how the social environment can affect risk for psychological problems like depression, anxiety, and suicidal behavior – and, in turn, how those psychological problems affect our risk for other kinds of poor health outcomes. Current research examines the causes and long-term health consequences of suicidal behavior.Past Research Topics:
Translating mathematical and computational understanding of biological systems to predict strategies for controlling or optimizing processes such as transport within cells, metastasizing tumors, division & growth in bacteria to aid development of therapeutic interventions.Past Research Topics:
The Biomechanics and Mechano-biology program focuses on research in core areas of Mechanics, Dynamics or Controls with applications to Biology and Medicine:
Stem cells are undifferentiated cells critical for embryonic development, adult tissue maintenance and injury repair. Stem cells play essential role in cancer and degenerative diseases, but the molecular basis regulating their behavior remains poorly understood. Our group investigates the fundamental mechanisms of stem cell regulation to gain insights on the process of regeneration, malignant cell transformation and the renewal of adult tissues.Past Research Topics:
Understanding the evolutionary processes which drive the emergence of antibiotic resistant pathogens and develop new strategies to combat them:
Understanding processes and developing the means to inform individuals, from teens to policy makers, to make better decisions that impact their health. Current research focuses specifically on:
Health and illness occur in the context of daily family life; by understanding these processes, we have the potential to promote better health, better illness management, and better family relationships.