My name is Brandon Imstepf, an applied mathematician with a focus on mathematical neuroscience. I model the transport and propagation of misfolded, pre- or post-pathological proteins in Alzheimer's Disease. I also develop and apply machine learning models to optimize (and/or at the very least, significantly speed up) methodologies within these models.
I am currently (09/2024) applying a machine learning model to simulation data with pathological tau flux between individual neurons in an attempt to replace a complicated and slow partial differential equation with a fast and accurate polynomial. This has the potential to completely overhaul the landscape of neurological modeling by bridging the scales between micro (protein-protein) and macro (whole brain) models, allowing for a complete, high resolution model of pathology.
